Abstract: A high efficient SCR denitrification technology was used to establish a bypass experiment device to treat NOx exhaust gas in the production of acrylonitrile catalysts, and the process conditions were optimized. In the catalytic filter assembly used, the mass composition of the catalyst was V2O5 (1%-5%), WO3 (5%-10%), MoO3 (5%-10%) and the rest was TiO2. Results showed that NOx conversion rate could reach 95% under the conditions of reaction temperature 320 ℃, molar ratio of NH3 to NOx 1.5, gas hourly space velocity (GHSV) 2 000 h-1 and atmospheric pressure. The NOx concentration in the exhaust emissions was less than 75 mg/m3 which was in compliance with the state and Shanghai emissions standards. The efficient SCR denitrification technology can be used for the NOx exhaust gas treatment of acrylonitrile catalyst production plant.