Application of Zwitterionic Materials in Biochemical Industry
GENG Yiwan1,2, YANG Jun1, WU Yanyue 1,2, QIU Xinyu3, WANG Wenli4, LU Zhiguo1, ZHANG Xin1
1. National Key Lab of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China;
2. University of Chinese Academy of Sciences, Beijing 100049, China;
3. Shandong First Medical University, Tai'an 271000, China;
4. Hebei Medical University, Shijiazhuang 050017, China
Abstract：Zwitterionic structure is electrically neutral with the same number of cationic and anionic functional groups. Materials with zwitterionic group exhibit outstanding anti-fouling characteristics due to the super hydration layer formed between water molecules. In addition, zwitterionic materials also have properties such as adhesion, frost resistance, enhanced drug solubility and ion selectivity, which extend the application to biomedical, industrial production and other fields. This paper focused on the application of zwitterionic materials in biochemical industry. Firstly, the anti-fouling property of zwitterionic materials was summarized from the perspective of anti-fouling objects protein, bacteria and virus. Secondly, the application progress in medical sensors, drug delivery and separation membranes were introduced. Finally, the problems and challenges in the development of zwitterionic materials were discussed, and the application prospects of zwitterionic materials were prospected.
GENG Yiwan,YANG Jun,WU Yanyue et al. Application of Zwitterionic Materials in Biochemical Industry[J]. Chemical Reaction Engineering and Technology, 2023, 39(2): 166-182.
