Synthesis and Structure of Hydrophobically ModifiedPolysulfobetaine Methacrylate
MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
Abstract：Hydrophobically modified polysulfobetaines exhibit superhydrophilicity, anti-protein adsorption and are environmentally friendly, which have potential applications in drug delivery, cosmetic, organ transplantation, food packaging and so on. In this work, polysulfobetaine methacrylate (PSBMA) hydrophobically modified with methacrylic acid 2,3-epoxypropyl ester (GMA) was synthesized via a free radical micellar copolymerization method. Effect of reaction condition upon the properties of the copolymer such as apparent viscosity of the copolymer aqueous solution and the yield were investigated. Experimental results showed that the content of SBMA was higher as the content of initiator was increased. When GMA content was low, the amount of SBMA decreased with increasing surfactant amount. However, the amount of SBMA was slightly influenced by the amount of surfactant in the case of high content GMA. Both the viscosity of the copolymer aqueous solution and the SBMA content decreased with the increase of stirring speed. The length and content of hydrophobic block segments were enlarged as GMA content was increased. Under the same ratio of SBMA/GMA monomers, increasing the amount of emulsifier increased the amount of GMA micelle and the content of hydrophobic block in copolymer. P(SBMA-GMA) copolymer chains were in the form of micelles in water, and the number molecular weight of P(SBMA-GMA) was higher than that of PSBMA.
Ma Yanjie,Wang Ping,Du Miao et al. Synthesis and Structure of Hydrophobically ModifiedPolysulfobetaine Methacrylate[J]. 化学反应工程与工艺, 2015, 31(3): 271-276.
