Abstract:This article summarized the application of Computational Fluid Dynamics (CFD) modeling for typical petrochemical processes such as fluid catalytic cracking, catalytic reforming and hydrocarbon pyrolysis. According to the characteristics of flow, transport and reactions, mathematical models were developed with CFD modeling approaches to accurately describe the reactor’s performance and were used to simulate and analyze the industrial reactors. The information about the velocity, temperature and species concentration distribution was then obtained, representing the flow, transport and reaction behaviors and their coupling mechanisms, which were used for rational process design, problem diagnosis and operation optimization of industrial processes.