Research Progress on Palladium Catalysts in the Heck Reaction
GUO Jin1, ZHAO Jinqi2, LI Xuesong2, ZHOU Mingdong2
1. SINOPEC (Dalian) Petrochemical Research Institute Company Limited, Dalian 116041, China;
2. College of Chemical Engineering, Shenyang University of Chemical Technology, Shenyang 110042, China
Abstract：The Heck reaction is a fundamental method for forming carbon-carbon bonds and is widely used in the synthesis of pharmaceuticals, pesticides, and functional materials. However, traditional homogeneous palladium catalytic systems face challenges, such as difficulty in separating and recovering the catalyst, residual precious metals, and poor cycle stability, which limit their large-scale industrial applications. To address this, this paper provides a systematic review of recent research progress on palladium catalysts supported on carriers such as carbon materials, metal oxides, non-metal oxides, polymers, and metal-organic frameworks. Owing to their high specific surface area, tunable pore structures, and easily modifiable surface chemistry, these supports effectively enhance the dispersion and catalytic activity of palladium species while significantly suppressing the leaching and agglomeration of palladium nanoparticles during the reaction, thereby improving the stability and cyclic performance of the catalyst. Despite these advances, the field still faces key challenges, such as the efficient activation of low-activity aryl chlorides and maintaining catalytic activity during long-term cycling. Future research could focus on the precise design and modification of active sites on the support surface, the development of green reaction media, and the scalable, controlled preparation of catalysts, to drive the Heck reaction towards greater efficiency, cost-effectiveness and sustainability.
GUO Jin,ZHAO Jinqi,LI Xuesong et al. Research Progress on Palladium Catalysts in the Heck Reaction[J]. Chemical Reaction Engineering and Technology, 2026, 42(3): 250-260.
