Synthesis Process of o-Nitroanisole over Triphase Transfer Catalysts
1. College of Chemistry and Chemical Engineering, Nanjing University of Technology, Nanjing 210009, China; 2. Institute of Chemical Defence, Beijing 102205, China
Abstract The triphase transfer catalyst PS-C5 was synthesized by polystyrene-o-divinylbenzene anion resin supported polyethylene glyol(PEG-400) and used to catalyze the o-nitroanisole (ONA) synthesis process from o-nitrochlorobenzene (ONCB). The influence of process conditions such as methanol amount, sodium hydroxide amount, catalyst dosage and reaction temperature on ONCB conversion were investigated. Under the better reaction conditions, such as ONCB 0.1mol, CH3OH 0.6mol, 40% NaOH 30 g, PS-C5 4 g, reaction temperature 70 ℃ and reaction time 10 h, the ONCB conversion reached 99.5% and the yield of ONA was 93.4%. The catalyst can be recovered easily and its catalytic performance is not decreased evidently for 6th used.
